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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f1b4d16edd3588744b014a25440657a20607c7b05294da8dffefdb897c005f' 
  AND token = 'H+3D1pcDrneJBMsAjSv75j7M73g61c9uof7/S24qgRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}