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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2846f8b3ac34eef732a82eaf7934764e91d46c958452afdd9d6f3d4d49b729a' 
  AND token = 'jAJgT/Bfsd4iL458U6Ns8oZOUaL56uPNYDpHVwHVhws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}