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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '060a2f15646a7b15703d65fd7254a8c21e01d73c59653fb9746ea027e254b62b' 
  AND token = 'yavL2tiz8hZVt2AGktRjzf2YlXx/CZ0nGcvHyOIgO0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}