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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c381aefb41afb927613c9d0a5bc19a42da8fc072e7c3c522e9f4ceb4ff833d0' 
  AND token = '2G1ph18r05zIpgMoWCWDgwkIgBcno6qwkGze+VX4ecM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}