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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21172995edd90253b3ce8aa09fdd3f306762f338ee0d0c94894d7bd47b30a51' 
  AND token = 'UL5DdQz5OKMB71TJwWPRRHeWPCLK6hSCPdd8ofsrlz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}