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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59219d0af384a216b41be000b25dce03865e29b38fa0563770331bd7785fc2bf' 
  AND token = 'd6mhAPmUbYo9Zv4B5r5QpQjDctvpb5aMUzyn+BVulEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}