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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b76d944f30f99fe3b082433e3e8da487565b3221b1273e3e0459c9ca0c8aa4' 
  AND token = 'c372eTI2L8qMTVL8j0iTzCW6KtMC5QdV55rYZ1eOFZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}