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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65c7444d2bb0db9cefae0cd0c0ab8f3fc2b800c43a4170af49db1c2553d8c68' 
  AND token = 'Zm9CYgeq7tu002+nOx5XHdB0gjjlt8r9j5etU9yy0CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}