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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21ba4fb4ec11419fca8b29938e8239f0b94647dfcd5dbe091cc88bc38e6202f' 
  AND token = 'CnJrgf2hES+SVa+VrlyzRGttbPoPSWXVO/dan0/CsBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}