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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef770b570ed946de897be8b49f8ba3d9042d9f6499d193184cae2aef64fe2da5' 
  AND token = 'UXpx1BsvT0ztpcjFlrZ2jqEHMw2/dSoBV8H216sQbSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}