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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193743c5ad5feb3aa9cdf55892b9a899fac03bd6d38edc24b4eaccd2c89aeead' 
  AND token = 'Mv+Dz6fWNiCXL9GflVTEy910c5fyOC4C5A/7TuPseyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}