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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a025f7a9f358b0467d547364198c9ed881f1a3bca9e1faca7d22c4aa2d78b5d' 
  AND token = 'gDeJNX+yRfw+b6g8QEjQwhfxIWfURce/6V2UwsRNw8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}