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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c693ce121eebb755393e2b4633a05352464cb98c447fd8d130dbcea13d5fd67a' 
  AND token = 'uw19i59beaPyiqdSRQ2RrUvkdgmmq9XZxw4S6WSmdNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}