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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ad4e375e83958b7187f2b37c05612822bf0d708d8b15705b72aef5b9486a24' 
  AND token = 'gynEf9Lhayu8e4W2bqimuZrtUs6PJEgmSF6Pu69cn/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}