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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fcdcb772658df7faf11bf538ea08a9ee0692b85828920cd9f00a1a11b27a39' 
  AND token = 'V0AYpiK2zwJxoERFAeE9dmvHwLO/GfstFis/VIMNeDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}