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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bde7f070b99489c0835ed2478183d3cd27a100b9797c02cb8a4f4d4dcc1a5ff' 
  AND token = 'mLqEWOfqdnFtupEIlRGPsurcc6Z7hjHPadATZsh17Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}