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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a44899907c4528bf3c47c6dd375fa34c1e2b931af473999ae3793eaed4fc0c64' 
  AND token = 'x38W0GPZsVSDblRgqaCEK19GXr9+IXg9CyT57eiizKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}