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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc20458878f9631e111f9e8e0b0fe1b72d88cce1ec2dd5acb999db2a177c22b' 
  AND token = 'GiAcJUzDoRHzYC9SwZi4hz8UK8wBN4UdKPDmfD3Phmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}