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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bb49a963733a6dff2910be19ec911a1c2736e094b0c7d6e1b133fd585a17248' 
  AND token = 'mI5bzJQE5S5Mbf1zXN48UvBxUSdlIMhvqiv8W/LogQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}