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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed621208bb528508ec0c66f2f80ed300e1bd9d5264597e51f0179df186d5f8b' 
  AND token = '1ruT5D4aSOUH8dsOBXbXjIJx0yEiQI/D6TuivaDoCIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}