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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e6c99784c3795a60a8b1d842a00929b608cc3d587e1ce86af4ede256d915c9' 
  AND token = 'HctmznGLuKm8cJROHWiE2pcTiDyZpgSIjIr4TgKo0pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}