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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3257ccaad55ab79486fc586d1a9048be45de3747cf6fcad6234687ad7bd4f55f' 
  AND token = 'Phg9tCJTpSel8oVKOS5doEn8GbnplER6PV5fvvvOXL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}