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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb4c47b9f7e184f5e25bb3d670464c7d1b904921d4d9de41e03d996fd0da5a4f' 
  AND token = 'cxWZYVKpxnFt6BssxM1CEwsc7UBHGBVAqUf1+l7GcsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}