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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229eb66eb2825b390aa7605f0971cb73bf3519d3287e175df1f68323e1276436' 
  AND token = 'LvDDotHsNLulL5xDHaSPmonqoQi7nOYFCq9SBjFI+Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}