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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a3b94bba162a74c603529cf665f4fa9f912dcded360e6629ddeddd0040666a' 
  AND token = 'tQc2Cbfxnu9pSJe0XrT5CbrcvAlPp7M14FnQ1bp8pyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}