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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f03639133572d8e01b88fd6a2abfe04efb30925b30765db99f76cb599e935d' 
  AND token = '1YBNfUoZp4nLF/FK+drZjgF2HCCfvFeHU3v0u4QrDI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}