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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c45e7c71d5d38293d5c57065acfae0862a292eecf4f63170120bb407ce0801' 
  AND token = 'aCGorS5ldmRdVVPDcs0m6vDSFK1umog7IzMKSQLA054=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}