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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48e4f0a43ffe1cd66f80f148acb3cbcdb7e5da144176cdb51b215fc1e7b01e5' 
  AND token = 'mIv+WN8yeVm8Z1EZVl1BQKzkaa5anQlyRY+MFiqadBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}