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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bed462bcd1d4d1d5a0a65b70032ab6c8e2d975bb814819c179d8e491b2bea82' 
  AND token = 'PnEssvX1KLhWOoe5dyyiBirss6PldAOlq8bOuksx76g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}