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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4c6117103a8dad29660e2cd3614ff936791b67e052df23fe631a982fe7ca68' 
  AND token = 'AwE7JCAIdmuAFfgcgO1sc718CLp843FKlc2p1+hAJ1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}