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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8df7ff10bfb6a41e8d03edfeb134ff1e087163ac7623f30ba05273fa8336900' 
  AND token = '8C+H1zDTsL5LUkNmWGz/EgllKIE2tnDdyGtF0ruflCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}