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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1fa7080c6b817acbe976e69d7bf176c1fc669a9b80139973a94d7300e67053' 
  AND token = 'YCPCOKgYp5RsYM4EUQtjeyi+LUBCK/jNtimultNIhKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}