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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cab49e646f17b267eb0480244fca46ba1a319c7519a36b7c41737a660b348d71' 
  AND token = 'VynFlpt2SBDqR2+3TjrWxf2M6f4pbdz4nisdoXW4niU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}