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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22d0fb00d3e423a9e1d203b3f7eb57e601ccf27b45597f132e9c63ce0a5b7c6' 
  AND token = 'ToTqLyigBHKT/8tQ3oAV4TTFrt9od7g0Ba4HnSgKEq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}