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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93e36850b9e71dc5054231ffba4a99951a019b67e79ce99090fd1487e148b36c' 
  AND token = 'wfv0W+UE7uEVFa5Cz3MbctuhYugpRV68snrbSteHWRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}