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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6f3c9c45e33076da46c281f5f60f22efe26ad46316e9bcd83be31c0bd90f8f' 
  AND token = '+z5QgQeyXbcUnaKZTrjgW/p6zewimAYXZ5QA0ee8SPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}