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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6eac45a351b5994b03c06c3065835d87a39a19f1d9ffe38fbc86ac2fc71864' 
  AND token = 'k37y6sH/8D/qb2dC38NT0IiA97f0nwFJdnEvvkIBzmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}