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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a60006b662c4bb40b86b3d3c8608653aa79a00913b557e80cec77d9ad92059' 
  AND token = 'FGSd9418OideEqshBv081GU4EUIIP/0pZPs5XMo3a10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}