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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b0fcbd996298fc227306ae3cb9c961099bf50d6d22776af70234b99ee91893' 
  AND token = '0C7kfewzozsALVQVqWjJKchdFoBuTkPKgKyOZ9BNsfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}