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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2375c11db58f9793a0ca36819f1095622a7679e9fbbcd9f4ac0d3aad247a01' 
  AND token = '2yW8EOl81CSMVj6SnpK6N/v84doFTaIuWi9hrzf/qXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}