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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fee2cf15b668597bacb2c2963e4a55bbd0d12b531fcc33d6aebc5cce596bdc39' 
  AND token = 'hcHHH2MBUe7K8sW4H2pOhnb+XrLq3WeWOD1VcXNtFzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}