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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727529e82644cb5fe5d22db24b06d1e737e6f3eb344897e5c5d822a096522a9c' 
  AND token = 'jKTYqbrCSPjKwl1R290UYR3JU2KLxGkypvmbWLqoZx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}