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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e139d3eb999956aabafa8b720222d782d7a43391fe1f3cbaf1caf99f510e51' 
  AND token = '5HmZi/E/+9f9udDwdyO7NLP8YJpKUJOgntrjolXFSoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}