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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8109fd6c9cbb20182a69baf1d884d5478c960809e00295305c6e7febcf2d7d6d' 
  AND token = 'k1QSLjiurw6FTgTk2pfkK7OnJuaQFSQIah5llghhfAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}