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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533cd6785b3a3254dbad399ec7631480008bc8dfcda6fbd100104125ca0e9425' 
  AND token = 'UWxuXwFQGTzGy5e0OryR3JN+oyvjxapmA4uDw6VkwFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}