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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aced10a849524fefbbe0f068fd0a298e6dec7e05ae4f3540c05891d12f68afa' 
  AND token = '8lQodoVEOB7fB2Msm9poc/v3hq7csYSXUTWGWKJi9EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}