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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1278905b0729788d6a5aed0fb8715b9e50a8c2ef35b9a01e47d2521d3d7cdac7' 
  AND token = '4Juk4sEzAt2eFYhWMw6ABUvgChgy2LtNMAGbJbZ0X/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}