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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66b7299e1ee09ab1c2458bc9eca796857aba65cc62719be0b35e1b66b0f9aad' 
  AND token = 'dGXMLjsnfctXvJNL0uRp5MHUYARClQ+XHnMgCoEXmQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}