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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a5a43e89d4a00975587e6891f3b0e386bba76165b1cb7b8036e64a1a633019' 
  AND token = 'cSDXmYObScGi9CXv2OMqWSGMDMhRq6m/TRNWJ7Ka098=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}