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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a014ee5a23e089bf906c70795997aa9537dbc6e7e6151bc831e725373b0c5507' 
  AND token = 'IqZX4T+2/GGnoKt05pOPS5mUojdSLMGAUH7PD1mGxDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}